Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis

Cernunnos is involved in the nonhomologous end-joining (NHEJ) process during DNA double-strand break (DSB) repair. Here, we studied immunoglobulin (Ig) class switch recombination (CSR), a physiological process which relies on proper repair of the DSBs, in B cells from Cernunnos-deficient patients. T...

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Autores principales: Du, Likun, Peng, Roujun, Björkman, Andrea, Filipe de Miranda, Noel, Rosner, Cornelia, Kotnis, Ashwin, Berglund, Mattias, Liu, Chonghai, Rosenquist, Richard, Enblad, Gunilla, Sundström, Christer, Hojjat-Farsangi, Mohammad, Rabbani, Hodjattallah, Teixeira, Manuel R., Revy, Patrick, Durandy, Anne, Zeng, Yixin, Gennery, Andrew R., de Villartay, Jean-Pierre, Pan-Hammarström, Qiang
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280866/
https://ncbi.nlm.nih.gov/pubmed/22312109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110325
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