Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function

Mutations of MECP2 (Methyl-CpG Binding Protein 2) cause Rett syndrome. As a chromatin-associated multifunctional protein, how MeCP2 integrates external signals and regulates neuronal function remain unclear. Although neuronal activity-induced phosphorylation of MeCP2 at serine 421 (S421) has been re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Tao, Jifang, Hu, Keping, Chang, Qiang, Wu, Hao, Sherman, Nicholas E., Martinowich, Keri, Klose, Robert J., Schanen, Carolyn, Jaenisch, Rudolf, Wang, Weidong, Sun, Yi Eve
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660725/
https://ncbi.nlm.nih.gov/pubmed/19225110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811648106
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados