Caveolin-1 scaffold domain interacts with TRPC1 and IP(3)R3 to regulate Ca(2+) store release-induced Ca(2+) entry in endothelial cells

Caveolin-1 (Cav-1) regulates agonist-induced Ca(2+) entry in endothelial cells; however, how Cav-1 regulates this process is poorly understood. Here, we describe that Cav-1 scaffold domain (NH(2)-terminal residues 82–101; CSD) interacts with transient receptor potential canonical channel 1 (TRPC1) a...

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Detalhes bibliográficos
Main Authors: Sundivakkam, Premanand C., Kwiatek, Angela M., Sharma, Tiffany T., Minshall, Richard D., Malik, Asrar B., Tiruppathi, Chinnaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660268/
https://ncbi.nlm.nih.gov/pubmed/19052258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00470.2008
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