Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cβ2 in the regulation of physiologic developmental hypertrophy and heart function

The phosphoinositide 3-kinase (PI3-kinase)-protein kinase B (Akt) signaling pathway is essential in the induction of physiological cardiac hypertrophy. In contrast, protein kinase C β2 (PKCβ2) is implicated in the development of pathological cardiac hypertrophy and heart failure. Thus far, no clear...

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Detalhes bibliográficos
Main Authors: Rigor, Debra L., Bodyak, Natalya, Bae, Soochan, Choi, Jun H., Zhang, Li, Ter-Ovanesyan, Dmitry, He, Zhiheng, McMullen, Julie R., Shioi, Tetsuo, Izumo, Seigo, King, George L., Kang, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Translational Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660227/
https://ncbi.nlm.nih.gov/pubmed/19122165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00562.2008
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