Role of cytosolic NADP(+)-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney

Cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) synthesizes reduced NADP (NADPH), which is an essential cofactor for the generation of reduced glutathione (GSH), the most abundant and important antioxidant in mammalian cells. We investigated the role of IDPc in kidney ischemia-reperfusio...

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Главные авторы: Kim, Jinu, Kim, Ki Young, Jang, Hee-Seong, Yoshida, Takumi, Tsuchiya, Ken, Nitta, Kosaku, Park, Jeen-Woo, Bonventre, Joseph V., Park, Kwon Moo
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660191/
https://ncbi.nlm.nih.gov/pubmed/19106211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90566.2008
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