Role of cytosolic NADP(+)-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney

Cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) synthesizes reduced NADP (NADPH), which is an essential cofactor for the generation of reduced glutathione (GSH), the most abundant and important antioxidant in mammalian cells. We investigated the role of IDPc in kidney ischemia-reperfusio...

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Hlavní autoři: Kim, Jinu, Kim, Ki Young, Jang, Hee-Seong, Yoshida, Takumi, Tsuchiya, Ken, Nitta, Kosaku, Park, Jeen-Woo, Bonventre, Joseph V., Park, Kwon Moo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660191/
https://ncbi.nlm.nih.gov/pubmed/19106211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90566.2008
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