Role of cytosolic NADP(+)-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney

Cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) synthesizes reduced NADP (NADPH), which is an essential cofactor for the generation of reduced glutathione (GSH), the most abundant and important antioxidant in mammalian cells. We investigated the role of IDPc in kidney ischemia-reperfusio...

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Main Authors: Kim, Jinu, Kim, Ki Young, Jang, Hee-Seong, Yoshida, Takumi, Tsuchiya, Ken, Nitta, Kosaku, Park, Jeen-Woo, Bonventre, Joseph V., Park, Kwon Moo
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660191/
https://ncbi.nlm.nih.gov/pubmed/19106211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90566.2008
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