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NADP(+)-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione
Cadmium (Cd(2+)) is toxic to living organisms because it causes the malfunction of essential proteins and induces oxidative stress. NADP(+)-dependent cytosolic isocitrate dehydrogenase (IDH) provides reducing energy to counteract oxidative stress via oxidative decarboxylation of isocitrate. Intrigui...
Gorde:
| Argitaratua izan da: | J Biol Inorg Chem |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Berlin Heidelberg
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6060952/ https://ncbi.nlm.nih.gov/pubmed/29923039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-018-1581-5 |
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