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Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice
Liver fibrosis is characterized by excessive deposition of extracellular matrix in the liver during chronic injury. During early stages of this disease, cells begin to synthesize and secrete profibrotic proteins that stimulate matrix production and inhibit matrix degradation. Although it is clear th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660171/ https://ncbi.nlm.nih.gov/pubmed/19136383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90368.2008 |
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