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Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma

Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models. We tested combinations of 17-AAG with the HDAC inhibi...

詳細記述

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書誌詳細
主要な著者: Nguyen, Anne, Su, Le, Campbell, Belinda, Poulin, Neal M., Nielsen, Torsten O.
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659882/
https://ncbi.nlm.nih.gov/pubmed/19325926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/794901
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