Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma

Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models. We tested combinations of 17-AAG with the HDAC inhibi...

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Hauptverfasser: Nguyen, Anne, Su, Le, Campbell, Belinda, Poulin, Neal M., Nielsen, Torsten O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659882/
https://ncbi.nlm.nih.gov/pubmed/19325926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/794901
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