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Design of Dual Inhibitors of Histone Deacetylase 6 and Heat Shock Protein 90

[Image: see text] Histone deacetylase 6 (HDAC6) and heat shock protein 90 (Hsp90) are widely investigated anticancer drug targets. Importantly, several lines of evidence indicate that their regulation and activity are intimately linked, and that their combined inhibition may lead to impressive thera...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Pinzi, Luca, Benedetti, Rosaria, Altucci, Lucia, Rastelli, Giulio
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254527/
https://ncbi.nlm.nih.gov/pubmed/32478236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00559
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