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Design of Dual Inhibitors of Histone Deacetylase 6 and Heat Shock Protein 90

[Image: see text] Histone deacetylase 6 (HDAC6) and heat shock protein 90 (Hsp90) are widely investigated anticancer drug targets. Importantly, several lines of evidence indicate that their regulation and activity are intimately linked, and that their combined inhibition may lead to impressive thera...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Pinzi, Luca, Benedetti, Rosaria, Altucci, Lucia, Rastelli, Giulio
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254527/
https://ncbi.nlm.nih.gov/pubmed/32478236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00559
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