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Targeting Histone Deacetylases in Diseases: Where Are We?
Significance: Epigenetic inactivation of pivotal genes involved in cell growth is a hallmark of human pathologies, in particular cancer. Histone acetylation balance obtained through opposing actions of histone deacetylases (HDACs) and histone acetyltransferases is one epigenetic mechanism controllin...
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Publicado no: | Antioxid Redox Signal |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4492558/ https://ncbi.nlm.nih.gov/pubmed/24382114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5776 |
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