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Targeting Histone Deacetylases in Diseases: Where Are We?

Significance: Epigenetic inactivation of pivotal genes involved in cell growth is a hallmark of human pathologies, in particular cancer. Histone acetylation balance obtained through opposing actions of histone deacetylases (HDACs) and histone acetyltransferases is one epigenetic mechanism controllin...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Benedetti, Rosaria, Conte, Mariarosaria, Altucci, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492558/
https://ncbi.nlm.nih.gov/pubmed/24382114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5776
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