Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma

Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat shock protein 90 (Hsp90) inhibitor 17-AAG have recently been shown to inhibit synovial sarcoma in preclinical models. We tested combinations of 17-AAG with the HDAC inhibi...

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Hlavní autoři: Nguyen, Anne, Su, Le, Campbell, Belinda, Poulin, Neal M., Nielsen, Torsten O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659882/
https://ncbi.nlm.nih.gov/pubmed/19325926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/794901
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