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BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/C(Cdc20) in Interphase
BubR1 is an essential mitotic checkpoint protein with multiple functional domains. It has been implicated in mitotic checkpoint control -as an active kinase at unattached kinetochores and as a cytosolic inhibitor of APC/C(Cdc20) activity- as well as in mitotic timing and stable chromosome-spindle at...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659634/ https://ncbi.nlm.nih.gov/pubmed/19154723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.11.004 |
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