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BubR1 N Terminus Acts as a Soluble Inhibitor of Cyclin B Degradation by APC/C(Cdc20) in Interphase

BubR1 is an essential mitotic checkpoint protein with multiple functional domains. It has been implicated in mitotic checkpoint control -as an active kinase at unattached kinetochores and as a cytosolic inhibitor of APC/C(Cdc20) activity- as well as in mitotic timing and stable chromosome-spindle at...

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Hlavní autoři: Malureanu, Liviu A., Jeganathan, Karthik B., Hamada, Masakazu, Wasilewski, Lisa, Davenport, James, van Deursen, Jan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659634/
https://ncbi.nlm.nih.gov/pubmed/19154723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.11.004
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