Cdc20 Is Critical for Meiosis I and Fertility of Female Mice

Chromosome missegregation in germ cells is an important cause of unexplained infertility, miscarriages, and congenital birth defects in humans. However, the molecular defects that lead to production of aneuploid gametes are largely unknown. Cdc20, the activating subunit of the anaphase-promoting com...

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Bibliografiske detaljer
Main Authors: Jin, Fang, Hamada, Masakazu, Malureanu, Liviu, Jeganathan, Karthik B., Zhou, Wei, Morbeck, Dean E., van Deursen, Jan M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947999/
https://ncbi.nlm.nih.gov/pubmed/20941357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001147
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