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Identification and characterization of small-molecule inhibitors of hepsin

Hepsin is a type-II transmembrane serine protease overexpressed in the majority of human prostate cancers. We recently demonstrated that hepsin promotes prostate cancer progression and metastasis and thus represents a potential therapeutic target. Here we report the identification of novel small-mol...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chevillet, John R., Park, Gemma J., Bedalov, Antonio, Simon, Julian A., Vasioukhin, Valeri I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659609/
https://ncbi.nlm.nih.gov/pubmed/18852137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0446
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