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Evaluation of α,β-unsaturated Ketone-based Probes for Papain-Family Cysteine Proteases

The field of activity based proteomics makes use of small molecule active site probes to monitor distinct subsets of enzymatic proteins. While a number of reactive functional groups have been applied to activity based probes (ABPs) that target diverse families of proteases, there remains a continual...

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Detalhes bibliográficos
Main Authors: Yang, Zhimou, Fonović, Marko, Verhelst, Steven H. L., Blum, Galia, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659416/
https://ncbi.nlm.nih.gov/pubmed/18343672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.02.089
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