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Efficient synthesis of β’-amino-α,β-unsaturated ketones

A general and simple procedure to access chiral β'-amino-α,β-enones, in seven steps, from an α,β unsaturated ester has been described. The use of a Horner–Wadsworth–Emmons reaction as a key step for generating the β'-amino-α,β-enones, permits access to a range of substrates under mild cond...

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Detalhes bibliográficos
Main Authors: Abrunhosa-Thomas, Isabelle, Plas, Aurélie, Kandepedu, Nishanth, Chalard, Pierre, Troin, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596044/
https://ncbi.nlm.nih.gov/pubmed/23504648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.52
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