Lineage specific composition of cyclin D–CDK4/CDK6–p27 complexes reveals distinct functions of CDK4, CDK6 and individual D‐type cyclins in differentiating cells of embryonic origin

Abstract.  Objectives: This article is to study the role of G(1)/S regulators in differentiation of pluripotent embryonic cells. Materials and methods: We established a P19 embryonal carcinoma cell‐based experimental system, which profits from two similar differentiation protocols producing endoderm...

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Detalhes bibliográficos
Main Authors: Bryja, V., Pacherník, J., Vondráček, J., Souček, K., Čajánek, L., Horvath, V., Holubcová, Z., Dvořák, P., Hampl, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659368/
https://ncbi.nlm.nih.gov/pubmed/19040567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2008.00556.x
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