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Phosphorylation of p27(Kip1) Regulates Assembly and Activation of Cyclin D1-Cdk4
p27 mediates Cdk2 inhibition and is also found in cyclin D1-Cdk4 complexes. The present data support a role for p27 in the assembly of D-type cyclin-Cdk complexes and indicate that both cyclin D1-Cdk4-p27 assembly and kinase activation are regulated by p27 phosphorylation. Prior work showed that p27...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577417/ https://ncbi.nlm.nih.gov/pubmed/18710949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02300-07 |
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