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Phosphorylation of Adaptor Protein–2 μ2 Is Essential for Na(+),K(+)-ATPase Endocytosis in Response to Either G Protein–Coupled Receptor or Reactive Oxygen Species
Activation of G protein–coupled receptor by dopamine and hypoxia-generated reactive oxygen species promote Na(+),K(+)-ATPase endocytosis. This effect is clathrin dependent and involves the activation of protein kinase C (PKC)-ζ and phosphorylation of the Na(+),K(+)-ATPase α-subunit. Because the inco...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Thoracic Society
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658693/ https://ncbi.nlm.nih.gov/pubmed/16498080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0044OC |
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