Histone H3 Lysine 36 Dimethylation (H3K36me2) Is Sufficient to Recruit the Rpd3s Histone Deacetylase Complex and to Repress Spurious Transcription

Histone methylation is associated with both transcription activation and repression. However, the functions of different states of methylation remain largely elusive. Here, using methyl-lysine analog technology, we demonstrate that the histone deacetylase complex, Rpd3S, can distinguish the nucleoso...

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Autors principals: Li, Bing, Jackson, Jessica, Simon, Matthew D., Fleharty, Brian, Gogol, Madelaine, Seidel, Chris, Workman, Jerry L., Shilatifard, Ali
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Transcription, Chromatin, and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658090/
https://ncbi.nlm.nih.gov/pubmed/19155214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808220200
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