Neutralization of Interleukin-18 Ameliorates Ischemia/Reperfusion-induced Myocardial Injury

Ischemia/reperfusion (I/R) injury is characterized by the induction of oxidative stress and proinflammatory cytokine expression. Recently demonstrating that oxidative stress and TNF-α each stimulate interleukin (IL)-18 expression in cardiomyocytes, we hypothesized that I/R also induces IL-18 express...

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Hlavní autoři: Venkatachalam, Kaliyamurthi, Prabhu, Sumanth D., Reddy, Venkatapuram Seenu, Boylston, William H., Valente, Anthony J., Chandrasekar, Bysani
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658078/
https://ncbi.nlm.nih.gov/pubmed/19164288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808824200
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