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Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

Dying tumour cells can elicit a potent anticancer immune response by exposing the calreticulin (CRT)/ERp57 complex on the cell surface before the cells manifest any signs of apoptosis. Here, we enumerate elements of the pathway that mediates pre-apoptotic CRT/ERp57 exposure in response to several im...

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Detalhes bibliográficos
Main Authors: Panaretakis, Theocharis, Kepp, Oliver, Brockmeier, Ulf, Tesniere, Antoine, Bjorklund, Ann-Charlotte, Chapman, Daniel C, Durchschlag, Michael, Joza, Nicholas, Pierron, Gérard, van Endert, Peter, Yuan, Junying, Zitvogel, Laurence, Madeo, Frank, Williams, David B, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657583/
https://ncbi.nlm.nih.gov/pubmed/19165151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.1
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