Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

Experiments performed in mice revealed that anthracyclines stimulate immunogenic cell death that is characterized by the pre-apoptotic exposure of calreticulin (CRT) on the surface of dying tumor cells. Here, we determined whether CRT exposure at the cell surface (ecto-CRT) occurs in human cancer in...

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Autori principali: Wemeau, M, Kepp, O, Tesnière, A, Panaretakis, T, Flament, C, De Botton, S, Zitvogel, L, Kroemer, G, Chaput, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032293/
https://ncbi.nlm.nih.gov/pubmed/21368877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.82
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