Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Cancer cell death can be perceived as immunogenic by the host only when malignant cells emit immunostimulatory signals (so-called “damage-associated molecular patterns,” DAMPs), as they die in the context of failing adaptive responses to stress. Accumulating preclinical and clinical evidence indicat...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Fucikova, Jitka, Truxova, Iva, Hensler, Michal, Becht, Etienne, Kasikova, Lenka, Moserova, Irena, Vosahlikova, Sarka, Klouckova, Jana, Church, Sarah E., Cremer, Isabelle, Kepp, Oliver, Kroemer, Guido, Galluzzi, Lorenzo, Salek, Cyril, Spisek, Radek
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201098/
https://ncbi.nlm.nih.gov/pubmed/27802968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-731737
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