Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Cancer cell death can be perceived as immunogenic by the host only when malignant cells emit immunostimulatory signals (so-called “damage-associated molecular patterns,” DAMPs), as they die in the context of failing adaptive responses to stress. Accumulating preclinical and clinical evidence indicat...

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Publicado en:Blood
Autores principales: Fucikova, Jitka, Truxova, Iva, Hensler, Michal, Becht, Etienne, Kasikova, Lenka, Moserova, Irena, Vosahlikova, Sarka, Klouckova, Jana, Church, Sarah E., Cremer, Isabelle, Kepp, Oliver, Kroemer, Guido, Galluzzi, Lorenzo, Salek, Cyril, Spisek, Radek
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2016
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201098/
https://ncbi.nlm.nih.gov/pubmed/27802968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-731737
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