Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Cancer cell death can be perceived as immunogenic by the host only when malignant cells emit immunostimulatory signals (so-called “damage-associated molecular patterns,” DAMPs), as they die in the context of failing adaptive responses to stress. Accumulating preclinical and clinical evidence indicat...

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Pubblicato in:Blood
Autori principali: Fucikova, Jitka, Truxova, Iva, Hensler, Michal, Becht, Etienne, Kasikova, Lenka, Moserova, Irena, Vosahlikova, Sarka, Klouckova, Jana, Church, Sarah E., Cremer, Isabelle, Kepp, Oliver, Kroemer, Guido, Galluzzi, Lorenzo, Salek, Cyril, Spisek, Radek
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201098/
https://ncbi.nlm.nih.gov/pubmed/27802968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-731737
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