Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

Cancer cell death can be perceived as immunogenic by the host only when malignant cells emit immunostimulatory signals (so-called “damage-associated molecular patterns,” DAMPs), as they die in the context of failing adaptive responses to stress. Accumulating preclinical and clinical evidence indicat...

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Veröffentlicht in:Blood
Hauptverfasser: Fucikova, Jitka, Truxova, Iva, Hensler, Michal, Becht, Etienne, Kasikova, Lenka, Moserova, Irena, Vosahlikova, Sarka, Klouckova, Jana, Church, Sarah E., Cremer, Isabelle, Kepp, Oliver, Kroemer, Guido, Galluzzi, Lorenzo, Salek, Cyril, Spisek, Radek
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2016
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201098/
https://ncbi.nlm.nih.gov/pubmed/27802968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-08-731737
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