Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8

The exposure of calreticulin (CRT) on the surface of stressed and dying cancer cells facilitates their uptake by dendritic cells and the subsequent presentation of tumor-associated antigens to T lymphocytes, hence stimulating an anticancer immune response. The chemotherapeutic agent mitoxantrone (MT...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sukkurwala, A Q, Martins, I, Wang, Y, Schlemmer, F, Ruckenstuhl, C, Durchschlag, M, Michaud, M, Senovilla, L, Sistigu, A, Ma, Y, Vacchelli, E, Sulpice, E, Gidrol, X, Zitvogel, L, Madeo, F, Galluzzi, L, Kepp, O, Kroemer, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857625/
https://ncbi.nlm.nih.gov/pubmed/23787997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.73
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados