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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-κB signalling

The RING domain protein RNF11 is overexpressed in breast cancers and promotes tumour growth factor-beta (TGF-β) signalling. RNF11 has been proposed to regulate TGF-β signalling by interacting with HECT- and SCF-type E3 ligases; however, the role of RNF11 in other signalling pathways is poorly unders...

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Autors principals: Shembade, Noula, Parvatiyar, Kislay, Harhaj, Nicole S, Harhaj, Edward W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657574/
https://ncbi.nlm.nih.gov/pubmed/19131965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.285
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