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Role of post-translational modifications of HTLV-1 Tax in NF-κB activation

Human T-cell leukemia virus type 1 (HTLV-1), the first human retrovirus discovered, is the etiological agent of adult-T-cell leukemia/lymphoma. The HTLV-1 encoded Tax protein is a potent oncoprotein that deregulates gene expression by constitutively activating nuclear factor-κB (NF-κB). Tax activati...

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Detalhes bibliográficos
Main Authors: Shembade, Noula, Harhaj, Edward W
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083931/
https://ncbi.nlm.nih.gov/pubmed/21540989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v1.i1.13
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