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The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation
The zinc finger-containing protein A20 is a negative regulator of TNF-induced JNK (c-Jun-N-terminal kinase) and NFκB (nuclear factor κB) signaling. A20 is an unusual enzyme that contains both ubiquitinating and deubiquitinating activities. Although A20 is mostly localized in the cytosol, our recent...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657479/ https://ncbi.nlm.nih.gov/pubmed/18952128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.09.013 |
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