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Inhibition of p97-dependent Protein Degradation by Eeyarestatin I
Elimination of misfolded proteins from the endoplasmic reticulum (ER) by ER-associated degradation involves substrate retrotranslocation from the ER lumen into the cytosol for degradation by the proteasome. For many substrates, retrotranslocation requires the action of ubiquitinating enzymes, which...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276333/ https://ncbi.nlm.nih.gov/pubmed/18199748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708347200 |
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