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Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3
Misfolded proteins of the endoplasmic reticulum undergo retrotranslocation to enter the cytosol where they are degraded by the proteasome. Retrotranslocation of many substrates requires an ATPase complex consisting of the p97 ATPase and a dimeric cofactor, Ufd1-Npl4. We report that efficient elimina...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064388/ https://ncbi.nlm.nih.gov/pubmed/17000876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605100 |
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