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Pre-TCR-Induced β-Catenin Facilitates Traversal through β-Selection

Pre-TCR induced signals regulate development of the αβ TCR lineage cells at the β-selection checkpoint. We have previously shown that conditional deletion of β-catenin, a central mediator of Wnt-β-catenin-T cell factor signaling pathway, impairs traversal through the β-selection checkpoint. We now p...

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Autors principals: Xu, Mai, Sharma, Archna, Wiest, David L., Sen, Jyoti Misra
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657338/
https://ncbi.nlm.nih.gov/pubmed/19124717
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