Minocycline and N-Methyl-4-Isoleucine Cyclosporin (NIM811) Mitigate Storage/Reperfusion Injury After Rat Liver Transplantation Through Suppression of the Mitochondrial Permeability Transition

Graft failure after liver transplantation may involve mitochondrial dysfunction. We examined whether prevention of mitochondrial injury would improve graft function. Orthotopic rat liver transplantation was performed after 18 hours' cold storage in University of Wisconsin solution and treatment...

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Hlavní autoři: Theruvath, Tom P., Zhong, Zhi, Pediaditakis, Peter, Ramshesh, Venkat K., Currin, Robert T., Tikunov, Andrey, Holmuhamedov, Ekhson, Lemasters, John J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656601/
https://ncbi.nlm.nih.gov/pubmed/18023036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.21912
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