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NIM811 Prevents Mitochondrial Dysfunction, Attenuates Liver Injury and Stimulates Liver Regeneration after Massive Hepatectomy,,

BACKGROUND: Massive hepatectomy (MHX) leads to failure of remnant livers. Excessive metabolic burden in remnant livers may cause mitochondrial dysfunction. This study investigated whether blockade of the mitochondrial permeability transition (MPT) with N-methyl-4-isoleucine cyclosporin (NIM811) impr...

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Detalhes bibliográficos
Main Authors: Rehman, Hasibur, Sun, Junjiang, Shi, Yanjun, Ramshesh, Venkat K., Liu, Qinglong, Currin, Robert T., Lemasters, John J., Zhong, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399729/
https://ncbi.nlm.nih.gov/pubmed/21131897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318204bdb2
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