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NIM811 Prevents Mitochondrial Dysfunction, Attenuates Liver Injury and Stimulates Liver Regeneration after Massive Hepatectomy,,

BACKGROUND: Massive hepatectomy (MHX) leads to failure of remnant livers. Excessive metabolic burden in remnant livers may cause mitochondrial dysfunction. This study investigated whether blockade of the mitochondrial permeability transition (MPT) with N-methyl-4-isoleucine cyclosporin (NIM811) impr...

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Bibliografske podrobnosti
Main Authors: Rehman, Hasibur, Sun, Junjiang, Shi, Yanjun, Ramshesh, Venkat K., Liu, Qinglong, Currin, Robert T., Lemasters, John J., Zhong, Zhi
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399729/
https://ncbi.nlm.nih.gov/pubmed/21131897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e318204bdb2
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