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Closure of VDAC Causes Oxidative Stress and Accelerates the Ca(2+)-induced Mitochondrial Permeability Transition in Rat Liver Mitochondria
The electron transport chain of mitochondria is a major source of reactive oxygen species (ROS), which play a critical role in augmenting the Ca(2+)-induced mitochondrial permeability transition (MPT). Mitochondrial release of superoxide anions (O(2)(•-)) from the intermembrane space (IMS) to the cy...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855314/ https://ncbi.nlm.nih.gov/pubmed/20097153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.01.008 |
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