Closure of VDAC Causes Oxidative Stress and Accelerates the Ca(2+)-induced Mitochondrial Permeability Transition in Rat Liver Mitochondria

The electron transport chain of mitochondria is a major source of reactive oxygen species (ROS), which play a critical role in augmenting the Ca(2+)-induced mitochondrial permeability transition (MPT). Mitochondrial release of superoxide anions (O(2)(•-)) from the intermembrane space (IMS) to the cy...

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Bibliografski detalji
Glavni autori: Tikunov, Andrey, Johnson, C. Bryce, Pediaditakis, Peter, Markevich, Nikolai, Macdonald, Jeffrey M., Lemasters, John J., Holmuhamedov, Ekhson
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855314/
https://ncbi.nlm.nih.gov/pubmed/20097153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.01.008
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