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Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes

NO and cGMP administered at reperfusion after ischaemia prevent injury to hepatocytes mediated by the MPT (mitochondrial permeability transition). To characterize further the mechanism of protection, the ability of hepatic cytosol in combination with cyclic nucleotides to delay onset of the calcium-...

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Detalhes bibliográficos
Main Authors: Pediaditakis, Peter, Kim, Jae-Sung, He, Lihua, Zhang, Xun, Graves, Lee M., Lemasters, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501339/
https://ncbi.nlm.nih.gov/pubmed/20738255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091741
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