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Reproductive functions of kisspeptin and Gpr54 across the life cycle of mice and men

The reproductive phenotypes of nearly two dozen patients with mutations in GPR54 have been reported, as have the phenotypes of four mouse lines mutant for Gpr54 and two lines mutant for Kiss1. These phenotypes demonstrate that kisspeptin/Gpr54 function is required at all phases of the life cycle whe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chan, Yee-Ming, Broder-Fingert, Sarabeth, Seminara, Stephanie B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656499/
https://ncbi.nlm.nih.gov/pubmed/18644412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.06.015
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