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Uncovering Novel Reproductive Defects in Neurokinin B Receptor Null Mice: Closing the Gap Between Mice and Men
Patients bearing mutations in TAC3 and TACR3 (which encode neurokinin B and its receptor, respectively) have sexual infantilism and infertility due to GnRH deficiency. In contrast, Tacr3(−/−) mice have previously been reported to be fertile. Because of this apparent phenotypic discordance between mi...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Endocrine Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281542/ https://ncbi.nlm.nih.gov/pubmed/22253416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1949 |
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