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Mimicking the folding pathway to improve homology-free protein structure prediction

Since the demonstration that the sequence of a protein encodes its structure, the prediction of structure from sequence remains an outstanding problem that impacts numerous scientific disciplines, including many genome projects. By iteratively fixing secondary structure assignments of residues durin...

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Bibliografiske detaljer
Main Authors: DeBartolo, Joe, Colubri, Andrés, Jha, Abhishek K., Fitzgerald, James E., Freed, Karl F., Sosnick, Tobin R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656149/
https://ncbi.nlm.nih.gov/pubmed/19237560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811363106
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