A Probabilistic and Continuous Model of Protein Conformational Space for Template-Free Modeling

One of the major challenges with protein template-free modeling is an efficient sampling algorithm that can explore a huge conformation space quickly. The popular fragment assembly method constructs a conformation by stringing together short fragments extracted from the Protein Data Base (PDB). The...

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Bibliographic Details
Main Authors: Zhao, Feng, Peng, Jian, Debartolo, Joe, Freed, Karl F., Sosnick, Tobin R., Xu, Jinbo
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203516/
https://ncbi.nlm.nih.gov/pubmed/20583926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2009.0235
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