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Mimicking the folding pathway to improve homology-free protein structure prediction

Since the demonstration that the sequence of a protein encodes its structure, the prediction of structure from sequence remains an outstanding problem that impacts numerous scientific disciplines, including many genome projects. By iteratively fixing secondary structure assignments of residues durin...

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Autori principali: DeBartolo, Joe, Colubri, Andrés, Jha, Abhishek K., Fitzgerald, James E., Freed, Karl F., Sosnick, Tobin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656149/
https://ncbi.nlm.nih.gov/pubmed/19237560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811363106
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