Mimicking the folding pathway to improve homology-free protein structure prediction

Since the demonstration that the sequence of a protein encodes its structure, the prediction of structure from sequence remains an outstanding problem that impacts numerous scientific disciplines, including many genome projects. By iteratively fixing secondary structure assignments of residues durin...

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Bibliographic Details
Main Authors: DeBartolo, Joe, Colubri, Andrés, Jha, Abhishek K., Fitzgerald, James E., Freed, Karl F., Sosnick, Tobin R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Physical Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656149/
https://ncbi.nlm.nih.gov/pubmed/19237560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811363106
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