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Mimicking the folding pathway to improve homology-free protein structure prediction

Since the demonstration that the sequence of a protein encodes its structure, the prediction of structure from sequence remains an outstanding problem that impacts numerous scientific disciplines, including many genome projects. By iteratively fixing secondary structure assignments of residues durin...

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Main Authors: DeBartolo, Joe, Colubri, Andrés, Jha, Abhishek K., Fitzgerald, James E., Freed, Karl F., Sosnick, Tobin R.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656149/
https://ncbi.nlm.nih.gov/pubmed/19237560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811363106
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