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ACTIVATED NOTCH SUPPORTS DEVELOPMENT OF CYTOKINE PRODUCING NK CELLS WHICH ARE HYPORESPONSIVE AND FAIL TO ACQUIRE NK CELL EFFECTOR FUNCTIONS
Natural Killer (NK) cells are powerful effectors of cytotoxicity against “stressed” cells. They also produce cytokines and chemokines to activate the adaptive immune response. Understanding NK cell development and maturation may have implications for cancer therapy and for immunity against infection...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2655654/ https://ncbi.nlm.nih.gov/pubmed/19167678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2008.11.031 |
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