A MT1-MMP/NF-κB signaling axis as a checkpoint controller of COX-2 expression in CD133(+) U87 glioblastoma cells

BACKGROUND: The CD133(+) stem cell population in recurrent gliomas is associated with clinical features such as therapy resistance, blood-brain barrier disruption and, hence, tumor infiltration. Screening of a large panel of glioma samples increasing histological grade demonstrated frequencies of CD...

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Autores principales: Annabi, Borhane, Laflamme, Carl, Sina, Asmaa, Lachambre, Marie-Paule, Béliveau, Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655289/
https://ncbi.nlm.nih.gov/pubmed/19272160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-8
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