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The lectin concanavalin-A signals MT1-MMP catalytic independent induction of COX-2 through an IKKγ/NF-κB-dependent pathway

The lectin from Canavalia ensiformis (Concanavalin-A, ConA), one of the most abundant lectins known, enables one to mimic biological lectin/carbohydrate interactions that regulate extracellular matrix protein recognition. As such, ConA is known to induce membrane type-1 matrix metalloproteinase (MT1...

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Detalhes bibliográficos
Main Authors: Sina, Asmaa, Proulx-Bonneau, Sébastien, Roy, Alain, Poliquin, Laurent, Cao, Jian, Annabi, Borhane
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821472/
https://ncbi.nlm.nih.gov/pubmed/20195390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-009-0084-0
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