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Necrosis Induction in Glioblastoma Cells Reveals a New “Bioswitch” Function for the MT1-MMP/G6PT Signaling Axis in proMMP-2 Activation versus Cell Death Decision

Cytoskeleton disorganization is an early step in the activation process of matrix metalloproteinase 2 (MMP-2) by membrane type 1 MMP (MT1-MMP) but is also associated with endoplasmic reticulum (ER) dysfunction and subsequent cell death. Given evidence that the ER-embedded glucose-6-phosphate transpo...

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Detalhes bibliográficos
Main Authors: Belkaid, Anissa, Fortier, Simon, Cao, Jian, Annabi, Borhane
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854846/
https://ncbi.nlm.nih.gov/pubmed/17460777
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