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A Concerted HIF-1α/MT1-MMP Signalling Axis Regulates the Expression of the 3BP2 Adaptor Protein in Hypoxic Mesenchymal Stromal Cells

Increased plasticity, migratory and immunosuppressive abilities characterize mesenchymal stromal cells (MSC) which enable them to be active participants in the development of hypoxic solid tumours. Our understanding of the oncogenic adaptation of MSC to hypoxia however lacks the identification and c...

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Autors principals: Proulx-Bonneau, Sébastien, Guezguez, Amel, Annabi, Borhane
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124525/
https://ncbi.nlm.nih.gov/pubmed/21738685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021511
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