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SCAMP3 Negatively Regulates Epidermal Growth Factor Receptor Degradation and Promotes Receptor Recycling

The epidermal growth factor receptor (EGFR) is targeted for lysosomal degradation by ubiquitin-mediated interactions with the ESCRTs (endosomal-sorting complexes required for transport) in multivesicular bodies (MVBs). We show that secretory carrier membrane protein, SCAMP3, localizes in part to ear...

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Autori principali: Aoh, Quyen L., Castle, Anna M., Hubbard, Charles H., Katsumata, Osamu, Castle, J. David
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655259/
https://ncbi.nlm.nih.gov/pubmed/19158374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0894
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